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B Cell Proliferation | © Edmond Alexander In bone marrow, macrophages, neutrophils, monocytes and other lymphocytes are activated by IL-10, granulocyte colony stimulating factor (G-CFS) and other cytokines to produce B-Lymphocyte stimulators (BLys) and proliferation-inducing ligands (APRIL) which mediate the survival, homeostasis and proliferation of Peripheral B cells.
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